Case study – Feasibility of microencapsulation of active ingredient by hydrogel microbead

Sector: Hygiene

Customer type: Group

Service contact: R&D

The Client wishes to use a highly hydrophilic and hygroscopic molecule as the active principle. He calls on RHEONIS to identify a suitable technical solution.

Identify and validate the feasibility of an encapsulation system

In response to this request, RHEONIS implemented its know-how of molecules of interest for encapsulation, processes mechanical and physico-chemical (extrusion simple, emulsification, spray-drying,…) as well as its experimental means.

The stages of the study were therefore as follows:

  1. Bibliographic research and definition of the system of interest
  2. Sourcing of raw materials
  3. Study of an adapted formulation protocol
  4. Development of laboratory-scale encapsulation protocols
  5. Feasibility tests and temporal monitoring of the release of the active ingredient
  6. Edition of a report of conclusions and outlook for further study
  7. Optimization of the formulation and the preparation and drying protocol with regard to application constraints
  8. Production of material for application tests by the Customer

Intervention System Gauge

Product & Ingredient 70%
Process & Application 70%
Measurement & Instrumentation 30%
Methods for Industry 50%

Identify optimal technical options in a competitive manner

This study has provided the Client in a short time with various encapsulation options that are scientifically viable, the most effective of which have been technically validated under laboratory conditions. Encapsulation efficiency has been confirmed and optimization routes have been identified.

The advantages of RHEONIS hybrid know-how

Knowledge of polymer systems

Accelerated literature review techniques for identifying options

Adapted, modular and efficient study resources

Strong sensitivity to industrial issues

Do you have any questions or would you like to discuss your encapsulation projects and issues with us? Do not hesitate to contact us.

Last Updated on February 14, 2022 by Vincent Billot